P. Leema Reddy, M.B.B.S., M.D.
Area of Specialty: Neurogenetics
Professional Appointments: Postdoctoral Fellow, Neurogenetics, New Jersey Neuroscience Institute, JFK Medical Center, Edison, New Jersey.
Medical Education and Research Experience: 2005- Till: Postdoctoral fellow, Neurogenetics, New Jersey Neuroscience Institute, JFK medical center, Edison, New Jersey. 2004:Postdoctoral fellow, Cellular and Synaptic Neurophysiology, New Jersey Neuroscience Institute, School of Graduate Medical education, Seton Hall University, South Orange, New Jersey. 1998-2004: M.D. in pharmacology, Dr. ALM Postgraduate Institute of Basic Medical Sciences, Taramani, University of Madras, Chennai, Tamilnadu, India. 1988-1995: Bachelor in Medicine and Bachelor in Surgery (M.B.B.S), Sri Venkateshwara Medical College, Tirupati, Dr. NTR University of Health Sciences, Andhra Pradesh, India. 1987-1988: Bachelor in Science, Sri Padmavathi Women's College, Tirupati, Sri Venkateshwara university, Andhra Pradesh, India.
Major Areas of Research:
Genetics of neurological diseases such as benign positional vertigo, hereditary spastic paraplegia and Stroke.
Study of neurodegenerative diseases such as Amyotrophic lateral sclerosis and epilepsy.
Establishing animal model for studying learning and memory and studying the effect of convulsions, anticonvulsants and the role of nitric oxide.
Affiliations in Professional Societies:
American society of Human Genetics
American Academy of Neurology
Society for Neuroscience
Representative Publications:
P. Leema Reddy , Raji P. Grewal. Possible Anticipation in Hereditary spastic paraplegia Type 4 (SPG4). Can. J. Neurol. Sci . 2007;34: 000-000
P. Leema Reddy , Raji P. Grewal. Hereditary spastic paraplegia 4 associated with polyneuropathy. Journal of Clinical Neuromuscular Disease , 2006. 8(2), December 2006, pp 99-100
P. Leema Reddy , Raji P. Grewal. Friedrich's ataxia: A clinical and genetic analysis. Clin Neurol Neurosurg . 2007 Feb;109(2):200-2. Epub 2006 Oct 17
Raji P. Grewal, P. Leema Reddy , Ana Virginia Dutra PhD, Michael Moussouttas MD, Nikolaos Papamitsakis MD. Genetic Analysis of the PDE4 gene in ischemic stroke. Journal of the New Jersey Neuroscience Institute . 2006; 1(1): 6-8
Ana Virginia Dutra, Hsiu-Fen Lin, Suh-Hang Hank Juo, Melanie Boyadis, Michael Moussouttas, P. Leema Reddy , Raji Paul Grewal. Analysis of the NOS-3 gene as a modifier of the cerebral response to ischemia. Journal of stroke and Cerebrovascular disease . 2006 may-June; 15(3):128131
Vanaja Paul , Leema Reddy , P. Ekambaram. A reversal by L-arginine and sodium nitroprusside of ageing-induced memory impairment in rats by increasing nitric oxide concentration in the hippocampus. Indian J Physiol Pharmacol . 2005 Apr; 49(2):179-86
Vanaja Paul , Leema Reddy , P. Ekambaram. The effect of L-arginine on the memory impairing action of phenobarbitone in rats that convulsed after the injection of picrotoxin. Indian J Physiol Pharmacol . 2004 Apr; 48(2):191-8
Vanaja Paul , Leema Reddy , P. Ekambaram. . Prevention of picrotoxin convulsions-induced learning and memory impairment by nitric oxide increasing dose of L-arginine in rats. Pharmacol Biochem Behav . 2003 May; 75(2):329-34
P. Leema Reddy , Karthik Rajasekaran, Vanaja Paul . Evidence for an involvement of nitric oxide in memory of shock avoidance task in rats. Indian J Physiol Pharmacol . 2002 Jan; 46(1):119-22
Karthik Rajasekaran , P. Leema Reddy , Vanaja Paul . Effect of systemically administered nitric oxide donor, sodium nitroprusside on picrotoxin-induced convulsions in rats . Indian J Physiol Pharmacol . 2001 Jan; 45(1):95-100